MuScle-logoMuScle - Molecule ID B0919

geneARFGAP1, ARF1GAP
nameADP-ribosylation factor GTPase activating protein 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARFG1_HUMANQ8N6T3ENSG0000010119955738Hs.25584608377

Functions and classifications

GOC:cytosol, C:endoplasmic reticulum, C:Golgi-associated vesicle membrane, C:nuclear membrane, C:plasma membrane, C:synapse, F:ARF GTPase activator activity, F:GTPase activator activity, F:zinc ion binding, P:activation of signaling protein activity involved in unfolded protein response, P:cellular protein metabolic process, P:COPI coating of Golgi vesicle, P:protein transport, P:regulation of ARF GTPase activity, P:retrograde vesicle-mediated transport, Golgi to ER, P:positive regulation of GTPase activity, C:Golgi membrane, F:metal ion binding
UniProt3D-structure, Acetylation, Alternative splicing, Complete proteome, Cytoplasm, ER-Golgi transport, Golgi apparatus, GTPase activation, Metal-binding, Phosphoprotein, Polymorphism, Protein transport, Reference proteome, Transport, Zinc, Zinc-finger
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_2_days_follow-up) (Multiple sclerosis)0.890.0435078320136355
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.171.10E-0222021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.253.87E-0422021740
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)0.796.26E-0322252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.682.34E-0322252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.114.98E-0223895517
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.183.29E-0423895517

Compile date 09-07-2016© MuScle project