MuScle-logoMuScle - Molecule ID B0907

geneADRBK2, BARK2, GRK3
nameBeta-adrenergic receptor kinase 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARBK2_HUMANP35626ENSG00000100077157Hs.657494109636

Functions and classifications

GOF:ATP binding, F:beta-adrenergic receptor kinase activity, F:G-protein coupled receptor kinase activity, F:protein kinase activity, P:receptor internalization, P:signal transduction, P:termination of G-protein coupled receptor signaling pathway, F:phospholipid binding
UniProtATP-binding, Complete proteome, Kinase, Nucleotide-binding, Polymorphism, Reference proteome, Serine/threonine-protein kinase, Transferase, Ubl conjugation, Receptor
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)1.569.05E-0317467740
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)2.317.81E-0317467740
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.884.31E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_2_days_follow-up) (Multiple sclerosis)0.872.74E-0220136355
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_12_month_follow-up) (Multiple sclerosis)1.480.0109864121886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.474.67E-0321886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.300.02712221886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.330.043217921886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_3_month_follow-up) (Multiple sclerosis)1.550.0016928821886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.222.09E-0322021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.228.10E-1222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.522.03E-0822252466

Compile date 09-07-2016© MuScle project