MuScle-logoMuScle - Molecule ID B0886

geneAQP4
nameAquaporin 4
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AQP4_HUMANP55087ENSG00000171885361Hs.315369600308

Functions and classifications

GOC:basolateral plasma membrane, C:cell-cell junction, C:cytoplasm, C:external side of plasma membrane, C:integral component of plasma membrane, C:protein complex, C:T-tubule, F:porin activity, F:water channel activity, P:carbon dioxide transport, P:cellular response to estradiol stimulus, P:cellular response to interferon-gamma, P:excretion, P:female pregnancy, P:hyperosmotic salinity response, P:multicellular organismal water homeostasis, P:nervous system development, P:protein homooligomerization, P:renal water absorption, P:response to glucocorticoid, P:response to radiation, P:sensory perception of sound, P:transmembrane transport, C:membrane, F:water transmembrane transporter activity, C:integral component of membrane, F:transporter activity, C:integral to plasma membrane, C:pore complex, C:integral to membrane
UniProt3D-structure, Alternative splicing, Complete proteome, Glycoprotein, Membrane, Phosphoprotein, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport, Ion transport, Porin
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.954.65E-0223895517
Exp24850724Homo sapiens12Blood CIS (Multiple sclerosis)0.340.0286003724850724

Compile date 09-07-2016© MuScle project