MuScle-logoMuScle - Molecule ID B0876

geneASPRV1, SASP
nameRetroviral-like aspartic protease 1 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
APRV1_HUMANQ53RT3ENSG00000244617151516Hs.516253611765

Functions and classifications

GOC:integral component of membrane, F:aspartic-type endopeptidase activity, P:protein processing, P:proteolysis, P:skin development, C:integral to membrane
UniProtAspartyl protease, Autocatalytic cleavage, Complete proteome, Direct protein sequencing, Glycoprotein, Hydrolase, Membrane, Polymorphism, Protease, Reference proteome, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)1.154.91E-0220136355
Exp21216829Homo sapiens8BloodCD4+RRMS_(CD4+) (Multiple sclerosis)6.630.029302321216829
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.253.63E-0222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.662.69E-0522252466
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)0.520.0183322622491253
Exp22491253Homo sapiens7Blood RRMS_(Low_Sema4A) (Multiple sclerosis)0.410.0454822491253
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.207.75E-0323895517

Compile date 09-07-2016© MuScle project