MuScle-logoMuScle - Molecule ID B0853

geneAPOB
nameApolipoprotein B-100 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
APOB_HUMANP04114ENSG00000084674338Hs.120759107730, 144010, 615558

Functions and classifications

GOC:chylomicron remnant, C:clathrin-coated endocytic vesicle membrane, C:cytosol, C:early endosome, C:endocytic vesicle lumen, C:endoplasmic reticulum lumen, C:endoplasmic reticulum membrane, C:endosome lumen, C:endosome membrane, C:intermediate-density lipoprotein particle, C:low-density lipoprotein particle, C:mature chylomicron, C:plasma membrane, C:very-low-density lipoprotein particle, F:cholesterol transporter activity, F:heparin binding, F:low-density lipoprotein particle receptor binding, F:phospholipid binding, P:artery morphogenesis, P:blood coagulation, P:cellular response to prostaglandin stimulus, P:cellular response to tumor necrosis factor, P:cholesterol efflux, P:cholesterol homeostasis, P:cholesterol metabolic process, P:fertilization, P:in utero embryonic development, P:leukocyte migration, P:lipoprotein biosynthetic process, P:lipoprotein catabolic process, P:lipoprotein metabolic process, P:lipoprotein transport, P:low-density lipoprotein particle clearance, P:low-density lipoprotein particle remodeling, P:nervous system development, P:phototransduction, visible light, P:positive regulation of cholesterol storage, P:positive regulation of macrophage derived foam cell differentiation, P:post-embryonic development, P:receptor-mediated endocytosis, P:regulation of cholesterol biosynthetic process, P:response to carbohydrate, P:response to lipopolysaccharide, P:response to selenium ion, P:response to virus, P:retinoid metabolic process, P:sperm motility, P:spermatogenesis, P:triglyceride catabolic process, P:triglyceride mobilization, P:very-low-density lipoprotein particle assembly, F:lipid transporter activity, C:endoplasmic reticulum, C:vesicle lumen, C:vesicle membrane, F:lipid binding, P:response to carbohydrate stimulus, P:cholesterol transport
UniProtAcetylation, Atherosclerosis, Cholesterol metabolism, Chylomicron, Complete proteome, Cytoplasm, Direct protein sequencing, Disease mutation, Disulfide bond, Glycoprotein, Heparin-binding, LDL, Lipid metabolism, Lipid transport, Lipoprotein, Palmitate, Polymorphism, Reference proteome, RNA editing, Secreted, Signal, Steroid metabolism, Sterol metabolism, Transport, VLDL
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.954.34E-0223895517

Compile date 09-07-2016© MuScle project