MuScle-logoMuScle - Molecule ID B0852

geneAPOA5, RAP3, UNQ411/PRO773
nameApolipoprotein A-V
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
APOA5_HUMANQ6Q788ENSG00000110243116519Hs.283923144650, 145750, 606368

Functions and classifications

GOC:chylomicron, C:high-density lipoprotein particle, C:very-low-density lipoprotein particle, F:enzyme binding, F:heparin binding, F:lipoprotein lipase activator activity, F:phosphatidylcholine binding, P:cholesterol homeostasis, P:lipid transport, P:lipoprotein metabolic process, P:organ regeneration, P:positive regulation of fatty acid biosynthetic process, P:positive regulation of lipoprotein lipase activity, P:positive regulation of receptor-mediated endocytosis, P:positive regulation of triglyceride catabolic process, P:positive regulation of very-low-density lipoprotein particle remodeling, P:response to hormone, P:small molecule metabolic process, P:tissue regeneration, P:triglyceride catabolic process, P:triglyceride homeostasis, P:triglyceride-rich lipoprotein particle remodeling, C:extracellular space, F:lipid binding, P:acylglycerol homeostasis, P:triglyceride metabolic process, C:extracellular region, P:response to hormone stimulus
UniProtChylomicron, Coiled coil, Complete proteome, Disease mutation, HDL, Lipid transport, Phosphoprotein, Polymorphism, Reference proteome, Secreted, Signal, Transport, VLDL, Lipoprotein
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)1.434.57E-0220136355
Exp21216829Homo sapiens8BloodCD4+RRMS_(CD4+) (Multiple sclerosis)3.460.037898421216829
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.963.61E-0222021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.912.81E-0222252466

Compile date 09-07-2016© MuScle project