MuScle-logoMuScle - Molecule ID B0846

geneAPLP2, APPL2, HSD-2
nameAmyloid-like protein 2 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
APLP2_HUMANQ06481ENSG00000084234334Hs.370247104776

Functions and classifications

GOC:integral component of membrane, C:nucleus, C:plasma membrane, F:DNA binding, F:heparin binding, F:serine-type endopeptidase inhibitor activity, F:transition metal ion binding, P:cellular copper ion homeostasis, P:cholesterol metabolic process, P:embryo development, P:extracellular matrix organization, P:forebrain development, P:G-protein coupled receptor signaling pathway, P:locomotory behavior, P:mating behavior, P:midbrain development, P:negative regulation of endopeptidase activity, P:neuromuscular process controlling balance, P:regulation of epidermal growth factor-activated receptor activity, P:regulation of protein binding, P:suckling behavior, C:integral to membrane
UniProtAlternative splicing, Cell membrane, Complete proteome, Disulfide bond, DNA-binding, Glycoprotein, Membrane, Nucleus, Polymorphism, Protease inhibitor, Reference proteome, Serine protease inhibitor, Signal, Transmembrane, Transmembrane helix
PADBINH: inhibitor (protease, kinase, other enzymes, pathways)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)0.642.02E-0217467740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.676.79E-0422021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.731.64E-0222021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.311.21E-0322021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.452.28E-0422021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.711.16E-0522021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)2.362.93E-0822021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)2.642.70E-0922021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)2.873.10E-0922021740
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)0.613.28E-0222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.331.58E-0522252466

Compile date 09-07-2016© MuScle project