MuScle-logoMuScle - Molecule ID B0834

geneANAPC7, APC7
nameAnaphase promoting complex subunit 7
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
APC7_HUMANQ9UJX3ENSG00000196510|ENSG0000025821051434Hs.719935606949

Functions and classifications

GOC:anaphase-promoting complex, C:cytosol, C:nucleoplasm, P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, P:mitosis, P:mitotic spindle assembly checkpoint, P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, P:protein K11-linked ubiquitination, P:cell division, P:mitotic cell cycle spindle assembly checkpoint
UniProt3D-structure, Alternative splicing, Cell cycle, Cell division, Complete proteome, Mitosis, Reference proteome, Repeat, TPR repeat, Ubl conjugation pathway
PADBCC: cell cycle (turnover, mitosis, meiosis)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)0.652.56E-0217467740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.893.73E-0222021740
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)0.811.91E-0222252466
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.390.01297622252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.681.56E-0522252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)2.041.85E-0822252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.171.90E-0423895517

Compile date 09-07-2016© MuScle project