MuScle-logoMuScle - Molecule ID B0831

geneAPC2, APCL
nameAdenomatous polyposis coli protein 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
APC2_HUMANO95996ENSG0000011526610297Hs.446376612034

Functions and classifications

GOC:actin filament, C:catenin complex, C:cytoplasmic microtubule, C:Golgi apparatus, C:Golgi membrane, C:lamellipodium membrane, C:perinuclear region of cytoplasm, F:beta-catenin binding, P:negative regulation of canonical Wnt signaling pathway, P:negative regulation of catenin import into nucleus, P:Wnt signaling pathway, P:negative regulation of canonical Wnt receptor signaling pathway, P:Wnt receptor signaling pathway, P:negative regulation of Wnt signaling pathway
UniProtAlternative splicing, Cell membrane, Coiled coil, Complete proteome, Cytoplasm, Cytoskeleton, Golgi apparatus, Membrane, Microtubule, Polymorphism, Reference proteome, Repeat, Wnt signaling pathway
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.974.37E-0222021740
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.190.018721422252466

Compile date 09-07-2016© MuScle project