MuScle-logoMuScle - Molecule ID B0827

geneANAPC11, HSPC214
nameAnaphase promoting complex subunit 11
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
APC11_HUMANQ9NYG5ENSG0000014155251529Hs.534456614534

Functions and classifications

GOC:anaphase-promoting complex, C:cytosol, C:nucleoplasm, F:ubiquitin-protein ligase activity, F:zinc ion binding, P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, P:mitosis, P:mitotic spindle assembly checkpoint, P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, P:protein K11-linked ubiquitination, F:metal ion binding, P:cell division, P:mitotic cell cycle spindle assembly checkpoint, P:protein ubiquitination
UniProtAlternative splicing, Cell cycle, Cell division, Complete proteome, Cytoplasm, Metal-binding, Mitosis, Nucleus, Reference proteome, Ubl conjugation, Ubl conjugation pathway, Zinc, Zinc-finger
PADBCC: cell cycle (turnover, mitosis, meiosis)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.833.22E-0221886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.223.13E-0422021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.732.82E-0622252466

Compile date 09-07-2016© MuScle project