MuScle-logoMuScle - Molecule ID B0826

geneANAPC10, APC10
nameAnaphase promoting complex subunit 10
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
APC10_HUMANQ9UM13ENSG0000016416210393Hs.480876613745

Functions and classifications

GOC:anaphase-promoting complex, C:cytosol, C:nucleoplasm, F:ubiquitin-protein ligase activity, P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, P:G2/M transition of mitotic cell cycle, P:mitosis, P:mitotic anaphase, P:mitotic spindle assembly checkpoint, P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, P:protein K11-linked ubiquitination, C:cytoplasm, P:cell division, P:mitotic cell cycle spindle assembly checkpoint
UniProt3D-structure, Acetylation, Cell cycle, Cell division, Complete proteome, Mitosis, Polymorphism, Reference proteome, Ubl conjugation pathway
PADBCC: cell cycle (turnover, mitosis, meiosis)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)1.361.20E-0320136355
Exp20921521Homo sapiens10Blood PPMS_(PRF1_gene_Risk_haplotype) (Multiple sclerosis)0.790.021625120921521
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.878.56E-0322021740
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.250.013269322252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.821.27E-0223895517

Compile date 09-07-2016© MuScle project