MuScle-logoMuScle - Molecule ID B0825

geneANAPC1, TSG24
nameAnaphase promoting complex subunit 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
APC1_HUMANQ9H1A4ENSG0000015310764682Hs.436527608473

Functions and classifications

GOC:anaphase-promoting complex, C:cytosol, C:nucleoplasm, P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, P:mitosis, P:mitotic spindle assembly checkpoint, P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, P:protein K11-linked ubiquitination, P:cell division, P:mitotic cell cycle spindle assembly checkpoint
UniProtCell cycle, Cell division, Complete proteome, Mitosis, Phosphoprotein, Reference proteome, Repeat, Ubl conjugation pathway
PADBCC: cell cycle (turnover, mitosis, meiosis)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.864.08E-0322021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.248.03E-0322252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.613.69E-0522252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)3.071.95E-0922252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.933.48E-0223895517

Compile date 09-07-2016© MuScle project