MuScle-logoMuScle - Molecule ID B0821

geneAPBB2, FE65L, FE65L1
nameAmyloid beta A4 precursor protein-binding family B member 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
APBB2_HUMANQ92870ENSG00000163697323Hs.479602602710

Functions and classifications

GOC:cytoplasm, C:growth cone, C:lamellipodium, C:membrane, C:nucleus, C:synapse, F:beta-amyloid binding, F:transcription factor binding, P:axon guidance, P:cell cycle arrest, P:extracellular matrix organization, P:intracellular signal transduction, P:negative regulation of apoptotic process, P:negative regulation of cell growth, P:neuron migration, P:positive regulation of apoptotic process, P:regulation of transcription, DNA-templated, P:negative regulation of S phase of mitotic cell cycle, P:regulation of transcription, DNA-dependent"
UniProtAlternative splicing, Complete proteome, Phosphoprotein, Polymorphism, Reference proteome, Repeat
PADBUK: unknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.700.0068090520136355
Exp21216829Homo sapiens8BloodCD4+RRMS_(CD4+) (Multiple sclerosis)12.130.032995521216829
Exp21216829Homo sapiens8BloodCD4+RRMS_(CD4+) (Multiple sclerosis)3.560.025067621216829
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)0.070.0412436521216829
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.943.60E-0222021740
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)2.550.0070757822491253
Exp22491253Homo sapiens7Blood RRMS_(Low_Sema4A) (Multiple sclerosis)0.440.046222922491253
Exp24850724Homo sapiens12Blood CIS (Multiple sclerosis)3.010.0223187724850724

Compile date 09-07-2016© MuScle project