MuScle-logoMuScle - Molecule ID B0820

geneAPBB1, FE65, RIR
nameAmyloid beta A4 precursor protein-binding family B member 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
APBB1_HUMANO00213ENSG00000166313322Hs.372840602709

Functions and classifications

GOC:cytoplasm, C:growth cone, C:lamellipodium, C:nuclear speck, C:nucleus, C:plasma membrane, C:synapse, F:beta-amyloid binding, F:chromatin binding, F:transcription factor binding, P:apoptotic process, P:axon guidance, P:axonogenesis, P:cell cycle arrest, P:cellular response to DNA damage stimulus, P:double-strand break repair, P:extracellular matrix organization, P:histone H4 acetylation, P:negative regulation of cell growth, P:negative regulation of neuron differentiation, P:negative regulation of thymidylate synthase biosynthetic process, P:neuron migration, P:positive regulation of apoptotic process, P:positive regulation of DNA repair, P:positive regulation of transcription from RNA polymerase II promoter, P:positive regulation of transcription, DNA-templated, P:signal transduction, P:transcription, DNA-templated, P:visual learning, "C:growth cone, P:regulation of transcription, DNA-templated", C:dendritic spine, C:perinuclear region of cytoplasm, C:postsynaptic membrane, C:presynaptic membrane, C:protein complex, P:negative regulation of S phase of mitotic cell cycle, P:positive regulation of protein secretion, P:positive regulation of transcription, DNA-dependent, P:response to DNA damage stimulus, P:response to iron ion, P:transcription, DNA-dependent, P:regulation of transcription, DNA-dependent"
UniProt3D-structure, Activator, Alternative splicing, Apoptosis, Cell membrane, Cell projection, Chromatin regulator, Complete proteome, Cytoplasm, DNA damage, Membrane, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Repressor, Transcription, Transcription regulation
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.573.02E-0221886806
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)0.711.89E-0222252466

Compile date 09-07-2016© MuScle project