MuScle-logoMuScle - Molecule ID B0798

geneAP2S1, AP17, CLAPS2
nameAP-2 complex subunit sigma
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AP2S1_HUMANP53680ENSG000000427531175Hs.119591600740, 602242

Functions and classifications

GOC:AP-2 adaptor complex, C:cytosol, F:protein transporter activity, P:antigen processing and presentation of exogenous peptide antigen via MHC class II, P:axon guidance, P:clathrin coat assembly, P:endocytosis, P:epidermal growth factor receptor signaling pathway, P:intracellular protein transport, P:negative regulation of epidermal growth factor receptor signaling pathway, P:neurotrophin TRK receptor signaling pathway, P:regulation of defense response to virus by virus, P:regulation of endocytosis, P:synaptic transmission, P:viral process, P:nerve growth factor receptor signaling pathway, P:viral reproduction, C:membrane coat, P:vesicle-mediated transport
UniProtAlternative splicing, Cell membrane, Coated pit, Complete proteome, Disease mutation, Endocytosis, Membrane, Phosphoprotein, Protein transport, Reference proteome, Transport
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.366.57E-0622021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.398.66E-0622021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.461.35E-0622021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.391.36E-1122252466

Compile date 09-07-2016© MuScle project