MuScle-logoMuScle - Molecule ID B0797

geneAP2M1, CLAPM1
nameAP-2 complex subunit mu
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AP2M1_HUMANQ96CW1ENSG000001612031173Hs.518460601024

Functions and classifications

GOC:clathrin adaptor complex, C:clathrin-coated endocytic vesicle membrane, C:coated pit, C:cytosol, C:lysosomal membrane, C:mitochondrion, C:plasma membrane, F:lipid binding, F:transporter activity, P:antigen processing and presentation of exogenous peptide antigen via MHC class II, P:axon guidance, P:endocytosis, P:epidermal growth factor receptor signaling pathway, P:intracellular protein transport, P:negative regulation of epidermal growth factor receptor signaling pathway, P:neurotrophin TRK receptor signaling pathway, P:regulation of defense response to virus by virus, P:synaptic transmission, P:viral process, P:vesicle-mediated transport, P:transport, C:clathrin coat of coated pit, P:cellular membrane organization, P:nerve growth factor receptor signaling pathway, P:viral reproduction
UniProt3D-structure, Alternative splicing, Cell membrane, Coated pit, Complete proteome, Endocytosis, Lipid-binding, Membrane, Phosphoprotein, Protein transport, Reference proteome, Transport
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)0.668.95E-0322252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.671.12E-0322252466

Compile date 09-07-2016© MuScle project