MuScle-logoMuScle - Molecule ID B0793

geneAP2B1, ADTB2, CLAPB1
nameAdapter-related protein complex 2 beta 1 subunit
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AP2B1_HUMANP63010ENSG00000006125|ENSG00000270478163Hs.514819601025

Functions and classifications

GOC:clathrin adaptor complex, C:clathrin-coated endocytic vesicle membrane, C:coated pit, C:cytosol, C:plasma membrane, C:trans-Golgi network, F:protein transporter activity, P:antigen processing and presentation of exogenous peptide antigen via MHC class II, P:axon guidance, P:clathrin coat assembly, P:endocytosis, P:epidermal growth factor receptor signaling pathway, P:intracellular protein transport, P:negative regulation of epidermal growth factor receptor signaling pathway, P:neurotrophin TRK receptor signaling pathway, P:regulation of defense response to virus by virus, P:synaptic transmission, P:viral process, P:vesicle-mediated transport, P:nerve growth factor receptor signaling pathway, P:neurotransmitter secretion, P:synaptic vesicle endocytosis, P:viral reproduction, C:membrane coat, C:clathrin coat
UniProt3D-structure, Acetylation, Alternative splicing, Cell membrane, Coated pit, Complete proteome, Endocytosis, Membrane, Phosphoprotein, Protein transport, Reference proteome, Transport
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)1.211.72E-0320136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_2_days_follow-up) (Multiple sclerosis)1.180.0062289720136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.140.0282765220136355
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.431.72E-0221886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)2.011.97E-0321886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.852.80E-0222021740
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)0.794.27E-0222252466
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.440.005561622252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.518.22E-0422252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)2.731.21E-0922252466

Compile date 09-07-2016© MuScle project