MuScle-logoMuScle - Molecule ID B0791

geneAP2A2, ADTAB, CLAPA2
nameAdapter-related protein complex 2 alpha 2 subunit
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AP2A2_HUMANO94973ENSG00000183020161Hs.19121607242

Functions and classifications

GOC:AP-2 adaptor complex, C:cytosol, F:lipid binding, F:protein transporter activity, P:antigen processing and presentation of exogenous peptide antigen via MHC class II, P:axon guidance, P:endocytosis, P:epidermal growth factor receptor signaling pathway, P:intracellular protein transport, P:negative regulation of epidermal growth factor receptor signaling pathway, P:neurotrophin TRK receptor signaling pathway, P:regulation of defense response to virus by virus, P:synaptic transmission, P:viral process, C:membrane coat, P:vesicle-mediated transport, C:clathrin adaptor complex, P:nerve growth factor receptor signaling pathway, P:viral reproduction, C:plasma membrane
UniProtAlternative splicing, Cell membrane, Coated pit, Complete proteome, Endocytosis, Lipid-binding, Membrane, Protein transport, Reference proteome, Transport, Phosphoprotein
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)1.727.81E-0317467740
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_2_days_follow-up) (Multiple sclerosis)0.910.0494334120136355
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)0.100.0015748221216829
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.123.33E-0323895517

Compile date 09-07-2016© MuScle project