MuScle-logoMuScle - Molecule ID B0790

geneAP2A1, ADTAA, CLAPA1
nameAdapter-related protein complex 2 alpha 1 subunit
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AP2A1_HUMANO95782ENSG00000196961160Hs.467125601026

Functions and classifications

GOC:AP-2 adaptor complex, C:apical plasma membrane, C:basolateral plasma membrane, C:clathrin coat of trans-Golgi network vesicle, C:cytosol, F:protein transporter activity, P:antigen processing and presentation of exogenous peptide antigen via MHC class II, P:axon guidance, P:endocytosis, P:epidermal growth factor receptor signaling pathway, P:Golgi to endosome transport, P:intracellular protein transport, P:negative regulation of epidermal growth factor receptor signaling pathway, P:neurotrophin TRK receptor signaling pathway, P:regulation of defense response to virus by virus, P:synaptic transmission, P:viral process, C:membrane coat, P:vesicle-mediated transport, C:clathrin adaptor complex, P:nerve growth factor receptor signaling pathway, P:viral reproduction
UniProtAlternative splicing, Cell membrane, Coated pit, Complete proteome, Endocytosis, Membrane, Phosphoprotein, Polymorphism, Protein transport, Reference proteome, Transport
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)1.651.48E-0317467740
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_6_month_follow-up) (Multiple sclerosis)1.561.02E-0217467740
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.713.61E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.730.0336187120136355
Exp21216829Homo sapiens8BloodCD4+RRMS_(CD4+) (Multiple sclerosis)12.210.005745721216829
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.831.09E-0222021740
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.190.023855622252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.611.79E-0522252466
Exp22491253Homo sapiens7Blood RRMS_(Low_Sema4A) (Multiple sclerosis)1.500.036201222491253
Exp22491253Homo sapiens7Blood RRMS_(Low_Sema4A) (Multiple sclerosis)2.960.004255322491253
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.134.30E-0223895517

Compile date 09-07-2016© MuScle project