MuScle-logoMuScle - Molecule ID B0787

geneAP1S2, DC22
nameAdapter-related protein complex 1 sigma 1B subunit
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AP1S2_HUMANP56377ENSG000001822878905Hs.121592300629, 300630, 603532

Functions and classifications

GOC:AP-type membrane coat adaptor complex, C:coated pit, C:cytoplasmic vesicle membrane, C:cytosol, C:Golgi membrane, C:lysosomal membrane, C:trans-Golgi network membrane, F:protein transporter activity, P:antigen processing and presentation of exogenous peptide antigen via MHC class II, P:intracellular protein transport, P:post-Golgi vesicle-mediated transport, P:regulation of defense response to virus by virus, P:viral process, C:membrane coat, P:vesicle-mediated transport, P:cellular membrane organization, P:endocytosis, P:viral reproduction
UniProtAlternative splicing, Coated pit, Complete proteome, Cytoplasmic vesicle, Golgi apparatus, Membrane, Mental retardation, Protein transport, Reference proteome, Transport, Endocytosis
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.892.49E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_2_days_follow-up) (Multiple sclerosis)0.884.76E-0220136355
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_12_month_follow-up) (Multiple sclerosis)1.360.0104897221886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.789.16E-0321886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.602.86E-0421886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.520.001324121886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_3_month_follow-up) (Multiple sclerosis)1.420.0027386321886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.114.09E-0222021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.134.04E-0222021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.525.82E-0622021740
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)0.843.86E-0222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.366.22E-1222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.381.06E-0922252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.881.78E-0223895517

Compile date 09-07-2016© MuScle project