MuScle-logoMuScle - Molecule ID B0780

geneAP1AR, PRO0971
nameGamma-1-adaptin Brefeldin A resistance protein
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AP1AR_HUMANQ63HQ0ENSG0000013866055435Hs.435991610851

Functions and classifications

GOC:early endosome, C:Golgi apparatus, C:late endosome, C:nucleolus, C:transport vesicle, F:AP-1 adaptor complex binding, F:kinesin binding, P:cellular protein localization, P:negative regulation of cell motility, P:negative regulation of receptor recycling, P:negative regulation of substrate adhesion-dependent cell spreading, P:protein transport, P:regulation of Arp2/3 complex-mediated actin nucleation, P:vesicle targeting, trans-Golgi to endosome, C:early endosome
UniProtAlternative splicing, Coiled coil, Complete proteome, Endosome, Glycoprotein, Golgi apparatus, Lipoprotein, Palmitate, Phosphoprotein, Polymorphism, Protein transport, Reference proteome, Transport
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.587.95E-0420136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_2_days_follow-up) (Multiple sclerosis)1.411.56E-0220136355
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.320.008728222252466
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.430.000432422252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.683.07E-0522252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.829.80E-0322252466

Compile date 09-07-2016© MuScle project