MuScle-logoMuScle - Molecule ID B0764

geneANXA2, ANX2, ANX2L4
nameAnnexin A2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ANXA2_HUMANP07355ENSG00000182718302Hs.511605151740

Functions and classifications

GOC:basement membrane, C:cell cortex, C:early endosome, C:extracellular vesicular exosome, C:extrinsic component of plasma membrane, C:lipid particle, C:macropinosome, C:melanosome, C:midbody, C:myelin sheath adaxonal region, C:perinuclear region of cytoplasm, C:protein complex, C:ruffle, C:sarcolemma, C:Schmidt-Lanterman incisure, F:calcium ion binding, F:calcium-dependent phospholipid binding, F:phosphatidylinositol-4,5-bisphosphate binding, F:phospholipase inhibitor activity, P:angiogenesis, P:body fluid secretion, P:cellular response to acid, P:collagen fibril organization, P:fibrinolysis, P:negative regulation of catalytic activity, P:positive regulation of binding, P:positive regulation of fibroblast proliferation, P:positive regulation of protein phosphorylation, P:positive regulation of vesicle fusion, P:protein targeting to plasma membrane, "C:cell cortex, C:vesicle, C:extrinsic to plasma membrane, C:plasma membrane, P:skeletal system development", "C:early endosome, P:positive regulation of binding"
UniProt3D-structure, Acetylation, Alternative splicing, Annexin, Basement membrane, Calcium, Calcium/phospholipid-binding, Complete proteome, Direct protein sequencing, Extracellular matrix, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Secreted, Ubl conjugation
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_6_month_follow-up) (Multiple sclerosis)0.654.93E-0217467740
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.531.43E-0221886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.572.17E-0221886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.582.10E-0221886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.142.23E-0222021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.142.74E-0222021740
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)0.692.37E-0222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.165.25E-1022252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.187.03E-0922252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.214.67E-0822252466
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)0.150.0198026822491253

Compile date 09-07-2016© MuScle project