MuScle-logoMuScle - Molecule ID B0710

geneANO6, TMEM16F
nameAnoctamin 6
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ANO6_HUMANQ4KMQ2ENSG00000177119196527Hs.505339262890, 608663

Functions and classifications

GOC:chloride channel complex, C:intracellular, C:plasma membrane, F:calcium activated cation channel activity, F:chloride channel activity, F:voltage-gated ion channel activity, P:activation of blood coagulation via clotting cascade, P:blood coagulation, P:chloride transmembrane transport, P:phosphatidylserine exposure on blood platelet, C:integral component of membrane
UniProtAlternative splicing, Cell membrane, Chloride, Chloride channel, Complete proteome, Glycoprotein, Ion channel, Ion transport, Membrane, Polymorphism, Reference proteome, Transmembrane, Transmembrane helix, Transport, Voltage-gated channel, Calcium
PADBCNL: channel

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21216829Homo sapiens8BloodCD4+RRMS_(CD4+) (Multiple sclerosis)3.480.008017121216829
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.188.20E-0322021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.677.02E-0422252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.791.17E-0422252466
Exp22491253Homo sapiens7Blood RRMS_(Low_Sema4A) (Multiple sclerosis)5.600.021047322491253

Compile date 09-07-2016© MuScle project