MuScle-logoMuScle - Molecule ID B0709

geneANO5, GDD1, TMEM16E
nameAnoctamin-5
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ANO5_HUMANQ75V66ENSG00000171714203859Hs.154329166260, 608662, 611307, 613319

Functions and classifications

GOC:endoplasmic reticulum membrane, C:integral component of membrane, C:intracellular, C:plasma membrane, P:ion transmembrane transport, C:chloride channel complex, F:chloride channel activity
UniProtCell membrane, Complete proteome, Disease mutation, Endoplasmic reticulum, Glycoprotein, Limb-girdle muscular dystrophy, Membrane, Osteogenesis imperfecta, Polymorphism, Reference proteome, Transmembrane, Transmembrane helix
PADBCNL: channel

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)1.602.57E-0220136355
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.361.39E-0221886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.330.014575521886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_3_month_follow-up) (Multiple sclerosis)1.700.0027122721886806
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.683.58E-0322252466

Compile date 09-07-2016© MuScle project