MuScle-logoMuScle - Molecule ID B0706

geneANO2, TMEM16B
nameAnoctamin-2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ANO2_HUMANQ9NQ90ENSG0000004761757101Hs.148970610109

Functions and classifications

GOC:chloride channel complex, C:nucleus, C:plasma membrane, F:intracellular calcium activated chloride channel activity, C:integral component of membrane, P:chloride transmembrane transport, F:chloride channel activity
UniProtAlternative splicing, Calcium, Cell membrane, Chloride, Chloride channel, Complete proteome, Glycoprotein, Ion channel, Ion transport, Membrane, Polymorphism, Reference proteome, Transmembrane, Transmembrane helix, Transport
PADBCNL: channel

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.224.12E-0220136355
Exp21216829Homo sapiens8BloodCD4+RRMS_(CD4+) (Multiple sclerosis)0.210.034499721216829

Compile date 09-07-2016© MuScle project