MuScle-logoMuScle - Molecule ID B0704

geneANO1, DOG1, ORAOV2
nameAnoctamin-1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ANO1_HUMANQ5XXA6ENSG0000013162055107Hs.503074610108

Functions and classifications

GOC:chloride channel complex, C:cytoplasm, C:plasma membrane, F:intracellular calcium activated chloride channel activity, P:multicellular organismal development, P:regulation of membrane potential, C:integral component of membrane, F:chloride channel activity
UniProtAlternative splicing, Calcium, Cell membrane, Chloride, Chloride channel, Complete proteome, Cytoplasm, Developmental protein, Glycoprotein, Ion channel, Ion transport, Membrane, Polymorphism, Reference proteome, Transmembrane, Transmembrane helix, Transport
PADBCNL: channel

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50BloodRRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)0.600.0363776320136355
Exp20136355Homo sapiens50BloodRRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.540.0055096320136355
Exp21886806Homo sapiens12BloodRRMS_(IFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)0.880.04081621886806
Exp22491253Homo sapiens7BloodRRMS_(High_Sema4A) (Multiple sclerosis)3.660.0417960322491253

Compile date 09-07-2016© MuScle project