MuScle-logoMuScle - Molecule ID B0685

geneANKRD1, CARP, HA1A2
nameAnkyrin repeat domain-containing protein 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ANKR1_HUMANQ15327ENSG0000014867727063Hs.448589106700, 609599

Functions and classifications

GOC:cytosol, C:I band, C:nucleoplasm, C:transcription factor complex, F:DNA binding, F:RNA polymerase II transcription coactivator activity, F:transcription corepressor activity, P:cardiac muscle tissue morphogenesis, P:cellular lipid metabolic process, P:cellular response to drug, P:cellular response to hypoxia, P:cellular response to interleukin-1, P:cellular response to lipopolysaccharide, P:cellular response to mechanical stimulus, P:cellular response to organic cyclic compound, P:cellular response to transforming growth factor beta stimulus, P:cellular response to tumor necrosis factor, P:negative regulation of DNA biosynthetic process, P:negative regulation of transcription from RNA polymerase II promoter, P:positive regulation of apoptotic process, P:positive regulation of DNA damage response, signal transduction by p53 class mediator, P:positive regulation of neuron projection development, P:positive regulation of protein secretion, P:response to muscle stretch, P:sarcomere organization, P:skeletal muscle cell differentiation, P:small molecule metabolic process
UniProtANK repeat, Coiled coil, Complete proteome, Disease mutation, Nucleus, Reference proteome, Repeat
PADBDIS: disease

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)0.330.0193679721216829
Exp24850724Homo sapiens12Blood CIS (Multiple sclerosis)2.990.0130782724850724

Compile date 09-07-2016© MuScle project