MuScle-logoMuScle - Molecule ID B0684

geneANKLE2, LEM4
nameAnkyrin repeat and LEM domain-containing protein 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
ANKL2_HUMANQ86XL3ENSG0000017691523141Hs.654628

Functions and classifications

GOC:integral component of endoplasmic reticulum membrane, F:protein phosphatase 2A binding, F:protein phosphatase type 2A regulator activity, P:mitosis, P:mitotic nuclear envelope reassembly, P:negative regulation of phosphorylation, P:positive regulation of protein dephosphorylation, C:cytoplasm, C:integral to endoplasmic reticulum membrane, C:nuclear envelope, P:cell division
UniProtAlternative splicing, ANK repeat, Cell cycle, Cell division, Complete proteome, Endoplasmic reticulum, Membrane, Mitosis, Phosphoprotein, Polymorphism, Reference proteome, Signal-anchor, Transmembrane, Transmembrane helix
PADBCC: cell cycle (turnover, mitosis, meiosis)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_2_days_follow-up) (Multiple sclerosis)1.130.019367820136355
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_12_month_follow-up) (Multiple sclerosis)0.880.044797221886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.878.50E-0322021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.182.80E-0322021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.294.99E-0522021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.828.76E-0722252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.104.26E-0223895517

Compile date 09-07-2016© MuScle project