MuScle-logoMuScle - Molecule ID B0676

nameAnkyrin 3
speciesHomo sapiens

Molecule reference


Functions and classifications

GOC:axon initial segment, C:basolateral plasma membrane, C:cell surface, C:costamere, C:dendrite, C:intercalated disc, C:lateral plasma membrane, C:lysosome, C:neuromuscular junction, C:node of Ranvier, C:paranode region of axon, C:postsynaptic membrane, C:sarcoplasmic reticulum, C:spectrin-associated cytoskeleton, C:T-tubule, C:Z disc, F:cadherin binding, F:ion channel binding, F:protein binding, bridging, F:spectrin binding, F:structural constituent of cytoskeleton, P:axon guidance, P:axonogenesis, P:Golgi to plasma membrane protein transport, P:maintenance of protein location in plasma membrane, P:membrane assembly, P:mitotic cytokinesis, P:neuromuscular junction development, P:positive regulation of cell communication by electrical coupling, P:positive regulation of gene expression, P:positive regulation of homotypic cell-cell adhesion, P:positive regulation of membrane depolarization involved in regulation of cardiac muscle cell action potential, P:positive regulation of membrane potential, P:positive regulation of protein targeting to membrane, P:positive regulation of sodium ion transmembrane transporter activity, P:positive regulation of sodium ion transport, P:protein targeting to plasma membrane, P:regulation of action potential in neuron, P:regulation of potassium ion transport, P:signal transduction, P:signal transduction, C:axon initial segment, C:endoplasmic reticulum, C:Golgi apparatus, P:cytoskeletal anchoring at plasma membrane, P:cytokinesis after mitosis, P:synapse organization", C:axon, C:synapse, P:synapse organization
UniProtAlternative splicing, ANK repeat, Cell junction, Cell membrane, Complete proteome, Cytoplasm, Cytoskeleton, Isopeptide bond, Lysosome, Membrane, Phosphoprotein, Polymorphism, Postsynaptic cell membrane, Reference proteome, Repeat, Synapse, Ubl conjugation
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.444.56E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.860.0351805520136355
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)0.230.0251232721216829

Compile date 09-07-2016© MuScle project