MuScle-logoMuScle - Molecule ID B0670

geneANGPT2, angiopoietin-2B, AGPT2
nameAngiopoietin-2 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ANGP2_HUMANO15123ENSG00000091879285Hs.583870601922

Functions and classifications

GOC:cell projection, C:extracellular space, C:nucleus, C:plasma membrane, F:metal ion binding, F:receptor binding, P:angiogenesis, P:blood coagulation, P:cellular response to growth factor stimulus, P:germ cell development, P:glomerulus vasculature development, P:leukocyte migration, P:maternal process involved in female pregnancy, P:negative regulation of angiogenesis, P:negative regulation of blood vessel endothelial cell migration, P:negative regulation of cell-substrate adhesion, P:negative regulation of positive chemotaxis, P:organ regeneration, P:positive regulation of angiogenesis, P:response to activity, P:response to glucose, P:response to hypoxia, P:response to mechanical stimulus, P:response to organic cyclic compound, P:response to radiation, P:Tie signaling pathway, P:response to glucose stimulus, P:Tie receptor signaling pathway, P:signal transduction
UniProt3D-structure, Alternative splicing, Angiogenesis, Calcium, Coiled coil, Complete proteome, Developmental protein, Differentiation, Disulfide bond, Glycoprotein, Metal-binding, Polymorphism, Reference proteome, Secreted, Signal
PADBSIG: signalling

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.640.0459954120136355
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)0.890.032422122252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.764.49E-0622252466
Exp22491253Homo sapiens7Blood RRMS_(Low_Sema4A) (Multiple sclerosis)5.780.022453422491253

Compile date 09-07-2016© MuScle project