MuScle-logoMuScle - Molecule ID B0629

geneAMY1B, AMY1A, AMY1
nameAlpha-amylase 1B, salivary precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AMY1_HUMANP04745ENSG00000174876|ENSG00000187733|ENSG00000237763276Hs.599274104700, 104701, 104702

Functions and classifications

GOC:extracellular region, F:alpha-amylase activity, F:metal ion binding, P:carbohydrate metabolic process, P:digestion, F:catalytic activity, "F:cation binding, F:hydrolase activity, acting on glycosyl bonds, P:carbohydrate metabolic process", F:cation binding
UniProt3D-structure, Calcium, Carbohydrate metabolism, Chloride, Complete proteome, Disulfide bond, Glycoprotein, Glycosidase, Hydrolase, Metal-binding, Pyrrolidone carboxylic acid, Reference proteome, Secreted, Signal
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)1.909.03E-0417467740
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_6_month_follow-up) (Multiple sclerosis)1.663.92E-0317467740
Exp20921521Homo sapiens10Blood PPMS_(PRF1_gene_Risk_haplotype) (Multiple sclerosis)1.630.019455120921521
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.774.11E-0322021740
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)1.543.94E-0222252466
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)0.730.031681522252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.852.75E-0223895517

Compile date 09-07-2016© MuScle project