MuScle-logoMuScle - Molecule ID B0627

geneAMBRA1
nameActivating molecule in BECN1-regulated autophagy protein 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AMRA1_HUMANQ9C0C7ENSG0000011049755626Hs.654644611359

Functions and classifications

GOC:autophagic vacuole, C:axoneme, C:cytoplasmic vesicle, P:autophagy, P:cell differentiation, P:negative regulation of cell proliferation, P:negative regulation of neuron apoptotic process, P:neural tube development, C:cytoplasm, P:positive regulation of apoptotic process
UniProtAlternative splicing, Autophagy, Complete proteome, Cytoplasmic vesicle, Developmental protein, Differentiation, Neurogenesis, Phosphoprotein, Reference proteome, Repeat, WD repeat
PADBDEV: development, cell growth, differentiation, morphogenesis

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)1.451.72E-0317467740
Exp20921521Homo sapiens10Blood PPMS_(PRF1_gene_Risk_haplotype) (Multiple sclerosis)0.650.00951720921521
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.172.10E-0221886806
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.637.46E-0822252466

Compile date 09-07-2016© MuScle project