MuScle-logoMuScle - Molecule ID B0606

geneAMFR, RNF45
nameE3 ubiquitin-protein ligase AMFR
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AMFR_HUMANQ9UKV5ENSG00000159461267Hs.295137603243

Functions and classifications

GOC:dendrite, C:growth cone, C:integral component of endoplasmic reticulum membrane, C:neuronal cell body, C:nucleus, F:receptor activity, F:ubiquitin-protein ligase activity, F:zinc ion binding, P:aging, P:cellular component movement, P:endoplasmic reticulum unfolded protein response, P:ER-associated ubiquitin-dependent protein catabolic process, P:learning or memory, P:protein oligomerization, P:protein polyubiquitination, C:cytoplasm, P:protein ubiquitination, C:integral to endoplasmic reticulum membrane, F:metal ion binding, P:ER-associated protein catabolic process
UniProt3D-structure, Complete proteome, Endoplasmic reticulum, Ligase, Membrane, Metal-binding, Phosphoprotein, Polymorphism, Receptor, Reference proteome, Transmembrane, Transmembrane helix, Ubl conjugation pathway, Zinc, Zinc-finger
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.326.72E-0322021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)2.735.83E-0322021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.376.15E-0422252466

Compile date 09-07-2016© MuScle project