MuScle-logoMuScle - Molecule ID B0603

geneAMER2, FAM123A
nameAPC membrane recruitment protein 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AMER2_HUMANQ8N7J2ENSG00000165566219287Hs.528335614659

Functions and classifications

GOC:plasma membrane, F:phosphatidylinositol-4,5-bisphosphate binding, P:ectoderm development, P:negative regulation of canonical Wnt signaling pathway, P:Wnt signaling pathway, P:negative regulation of canonical Wnt receptor signaling pathway, P:Wnt receptor signaling pathway"
UniProtAlternative splicing, Cell membrane, Complete proteome, Lipid-binding, Membrane, Phosphoprotein, Polymorphism, Reference proteome, Wnt signaling pathway
PADBSIG: signalling

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.455.31E-0320136355
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)10.770.0235150421216829
Exp21346816Homo sapiens12Blood MS (Multiple sclerosis)1.170.0458521346816
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.611.68E-0422252466

Compile date 09-07-2016© MuScle project