MuScle-logoMuScle - Molecule ID B0602

geneAMER1, FAM123B, WTX
nameAPC membrane recruitment protein 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AMER1_HUMANQ5JTC6ENSG00000184675139285Hs.314225300373, 300647

Functions and classifications

GOC:cytosol, C:nucleus, C:plasma membrane, F:beta-catenin binding, F:phosphatidylinositol-4,5-bisphosphate binding, P:adipose tissue development, P:bone development, P:mesenchymal cell differentiation involved in kidney development, P:negative regulation of canonical Wnt signaling pathway, P:positive regulation of canonical Wnt signaling pathway, P:Wnt signaling pathway, P:negative regulation of canonical Wnt receptor signaling pathway, P:positive regulation of canonical Wnt receptor signaling pathway, P:Wnt receptor signaling pathway"
UniProtAcetylation, Alternative splicing, Cell membrane, Complete proteome, Cytoplasm, Lipid-binding, Membrane, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Wnt signaling pathway
PADBSIG: signalling

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp21216829Homo sapiens8BloodCD8+RRMS_(CD8+) (Multiple sclerosis)0.150.0350397521216829
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.480.015839222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.794.46E-0522252466

Compile date 09-07-2016© MuScle project