MuScle-logoMuScle - Molecule ID B0587

geneALPK1, LAK
nameAlpha-protein kinase 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ALPK1_HUMANQ96QP1ENSG0000007333180216Hs.652825607347

Functions and classifications

GOF:ATP binding, F:protein serine/threonine kinase activity, F:kinase activity
UniProtAlternative splicing, Complete proteome, Kinase, Polymorphism, Reference proteome, Serine/threonine-protein kinase, Transferase
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.762.04E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.400.0035463420136355
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)1.713.88E-0321886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)1.390.018615921886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_3_month_follow-up) (Multiple sclerosis)1.430.0083408421886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.224.05E-0222021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.631.56E-0322252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.672.50E-0422252466
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)0.410.024907222491253

Compile date 09-07-2016© MuScle project