MuScle-logoMuScle - Molecule ID B0582

geneALKBH8, ABH8
nameAlkylated DNA repair protein alkB homolog 8
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ALKB8_HUMANQ96BT7ENSG0000013776091801Hs.503763613306

Functions and classifications

GOC:cytosol, C:microtubule cytoskeleton, C:nucleus, F:metal ion binding, F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, F:RNA binding, F:tRNA (uracil) methyltransferase activity, P:cellular response to DNA damage stimulus, "F:methyltransferase activity, P:methylation", F:nucleic acid binding, F:nucleotide binding, P:response to DNA damage stimulus"
UniProt3D-structure, Alternative splicing, Complete proteome, Cytoplasm, Iron, Metal-binding, Methyltransferase, Multifunctional enzyme, Nucleus, Oxidoreductase, Reference proteome, RNA-binding, S-adenosyl-L-methionine, Transferase
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50BloodRRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)1.332.44E-0320136355
Exp22021740Homo sapiens27BloodMS (Multiple sclerosis)0.822.18E-0222021740

Compile date 09-07-2016© MuScle project