MuScle-logoMuScle - Molecule ID B0581

geneALKBH7, ABH7, SPATA11
nameAlkylated DNA repair protein ALKB homolog 7 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ALKB7_HUMANQ9BT30ENSG0000012565284266Hs.111099613305

Functions and classifications

GOC:mitochondrial matrix, F:dioxygenase activity, F:metal ion binding, P:cellular response to DNA damage stimulus, P:fatty acid metabolic process, P:necrotic cell death, P:programmed cell death, P:regulation of lipid storage, "C:extracellular region, C:mitochondrion, C:nucleus, F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"
UniProtComplete proteome, Dioxygenase, Iron, Metal-binding, Mitochondrion, Necrosis, Oxidoreductase, Polymorphism, Reference proteome, Transit peptide, Cytoplasm, Nucleus, Secreted, Signal
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50BloodRRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.541.39E-0220136355
Exp20136355Homo sapiens50BloodRRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.785.11E-0420136355
Exp20136355Homo sapiens50BloodRRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.841.91E-0220136355
Exp20136355Homo sapiens50BloodRRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)0.872.21E-0220136355
Exp20136355Homo sapiens50BloodRRMS_(rIFN-Beta-1b_2_days_follow-up) (Multiple sclerosis)0.874.35E-0220136355
Exp20136355Homo sapiens50BloodRRMS_(rIFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.810.0008927620136355
Exp21886806Homo sapiens12BloodRRMS_(IFN-Beta-1a_12_month_follow-up) (Multiple sclerosis)0.740.0463391921886806
Exp21886806Homo sapiens12BloodRRMS_(IFN-Beta-1a_24_month_follow-up) (Multiple sclerosis)0.740.038773521886806
Exp21886806Homo sapiens12BloodRRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.724.12E-0221886806
Exp21886806Homo sapiens12BloodRRMS_(IFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)0.640.01214521886806
Exp21886806Homo sapiens12BloodRRMS_(IFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.640.017484221886806
Exp22021740Homo sapiens27BloodMS (Multiple sclerosis)1.197.99E-0322021740
Exp22021740Homo sapiens27BloodMS (Multiple sclerosis)1.432.14E-0522021740

Compile date 09-07-2016© MuScle project