MuScle-logoMuScle - Molecule ID B0579

geneALKBH5, ABH5, OFOXD1
nameAlkylated DNA repair protein ALKB homolog 5
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ALKB5_HUMANQ6P6C2ENSG0000009154254890Hs.744130613303

Functions and classifications

GOC:nuclear speck, F:metal ion binding, F:oxidative RNA demethylase activity, F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, P:cell differentiation, P:mRNA export from nucleus, P:mRNA processing, P:oxidative single-stranded RNA demethylation, P:response to hypoxia, P:spermatogenesis, "F:metal ion binding, F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"
UniProtAcetylation, Alternative splicing, Coiled coil, Complete proteome, Differentiation, Dioxygenase, Iron, Metal-binding, Nucleus, Oxidoreductase, Phosphoprotein, Reference proteome, Spermatogenesis
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.102.08E-0222021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)2.626.70E-0822021740
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.232.60E-0423895517

Compile date 09-07-2016© MuScle project