MuScle-logoMuScle - Molecule ID B0578

geneALKBH4, ABH4
nameAlkylated DNA repair protein ALKB homolog 4
speciesHomo sapiens

Molecule reference


Functions and classifications

GOC:contractile ring, C:midbody, C:mitochondrion, C:nucleus, F:actin binding, F:demethylase activity, F:metal ion binding, F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, P:actomyosin structure organization, P:cleavage furrow ingression, P:protein demethylation, P:regulation of transcription, DNA-templated, P:transcription, DNA-templated, "C:mitochondrion, F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"
UniProtAcetylation, Actin-binding, Alternative splicing, Complete proteome, Cytoplasm, Dioxygenase, Iron, Metal-binding, Nucleus, Oxidoreductase, Polymorphism, Reference proteome, Transcription, Transcription regulation
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.162.71E-0222021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.481.29E-0222252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.074.32E-0223895517

Compile date 09-07-2016© MuScle project