MuScle-logoMuScle - Molecule ID B0572

geneALG8, HUSSY-02
nameDolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3- glucosyltransferase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ALG8_HUMANQ9BVK2ENSG0000015906379053Hs.503368608103, 608104

Functions and classifications

GOC:endoplasmic reticulum membrane, C:integral component of membrane, F:alpha-1,3-mannosyltransferase activity, P:dolichol-linked oligosaccharide biosynthetic process, P:post-translational protein modification, P:protein N-linked glycosylation via asparagine, F:transferase activity, transferring hexosyl groups, P:metabolic process", C:integral to membrane, F:transferase activity, transferring hexosyl groups"
UniProtAlternative splicing, Complete proteome, Congenital disorder of glycosylation, Disease mutation, Endoplasmic reticulum, Glycosyltransferase, Membrane, Polymorphism, Reference proteome, Transferase, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20921521Homo sapiens10Blood PPMS_(PRF1_gene_Risk_haplotype) (Multiple sclerosis)0.730.041827520921521
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.543.33E-0522252466

Compile date 09-07-2016© MuScle project