MuScle-logoMuScle - Molecule ID B0564

geneALG12, PP14673, PP3999
nameDolichyl-p-Man:Man(7)GlcNAc(2)-PP-dolichyl mannosyltransferase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ALG12_HUMANQ9BV10ENSG0000018285879087Hs.526711607143, 607144

Functions and classifications

GOC:endoplasmic reticulum membrane, C:integral component of membrane, F:alpha-1,6-mannosyltransferase activity, F:dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity, P:dolichol-linked oligosaccharide biosynthetic process, P:post-translational protein modification, P:protein folding, P:protein N-linked glycosylation via asparagine, "F:transferase activity, transferring glycosyl groups, P:metabolic process", C:integral to membrane, C:intrinsic to endoplasmic reticulum membrane, P:GPI anchor biosynthetic process, "C:intrinsic to endoplasmic reticulum membrane, F:transferase activity, transferring glycosyl groups, P:GPI anchor biosynthetic process"
UniProtComplete proteome, Congenital disorder of glycosylation, Disease mutation, Endoplasmic reticulum, Glycosyltransferase, Membrane, Polymorphism, Reference proteome, Transferase, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.141.93E-0523895517

Compile date 09-07-2016© MuScle project