MuScle-logoMuScle - Molecule ID B0562

geneALG1, HMAT1, HMT1
nameChitobiosyldiphosphodolichol beta-mannosyltransferase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ALG1_HUMANQ9BT22ENSG0000003301156052Hs.592086605907, 608540

Functions and classifications

GOC:endoplasmic reticulum membrane, C:integral component of membrane, F:chitobiosyldiphosphodolichol beta-mannosyltransferase activity, F:mannosyltransferase activity, P:dolichol-linked oligosaccharide biosynthetic process, P:lipopolysaccharide biosynthetic process, P:post-translational protein modification, P:protein N-linked glycosylation via asparagine, "F:transferase activity, transferring glycosyl groups, P:metabolic process", C:integral to membrane, "F:transferase activity, transferring glycosyl groups", F:transferase activity, transferring glycosyl groups, P:metabolic process
UniProtComplete proteome, Congenital disorder of glycosylation, Disease mutation, Endoplasmic reticulum, Glycosyltransferase, Membrane, Phosphoprotein, Polymorphism, Reference proteome, Signal-anchor, Transferase, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.133.81E-0222021740
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)0.772.47E-0222252466
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.250.024595422252466
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)1.270.036243522252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.322.08E-0422252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)1.112.33E-0323895517

Compile date 09-07-2016© MuScle project