MuScle-logoMuScle - Molecule ID B0561

geneAKR1B1, ALDR1
nameAldose reductase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ALDR_HUMANP15121ENSG00000085662231Hs.521212103880

Functions and classifications

GOC:cytosol, C:extracellular space, C:nucleus, F:alditol:NADP+ 1-oxidoreductase activity, F:electron carrier activity, F:glyceraldehyde oxidoreductase activity, P:C21-steroid hormone biosynthetic process, P:carbohydrate metabolic process, P:daunorubicin metabolic process, P:doxorubicin metabolic process, P:response to stress, P:oxidation-reduction process, F:oxidoreductase activity, C:cytoplasm, P:small molecule metabolic process
UniProt3D-structure, Acetylation, Complete proteome, Cytoplasm, Direct protein sequencing, NADP, Oxidoreductase, Polymorphism, Reference proteome
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)0.850.0007914320136355
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_12_month_follow-up) (Multiple sclerosis)0.750.046113121886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.611.88E-0321886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)0.700.004921886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.590.011143121886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_3_month_follow-up) (Multiple sclerosis)0.640.0010653521886806
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.911.55E-0222252466

Compile date 09-07-2016© MuScle project