MuScle-logoMuScle - Molecule ID B0557

geneALDH2, ALDM
nameAldehyde dehydrogenase, mitochondrial precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ALDH2_HUMANP05091ENSG00000111275|ENSG00000257767217Hs.604551100650, 610251

Functions and classifications

GOC:mitochondrial matrix, F:aldehyde dehydrogenase (NAD) activity, F:aldehyde dehydrogenase [NAD(P)+] activity, F:electron carrier activity, P:carbohydrate metabolic process, P:ethanol catabolic process, P:ethanol oxidation, P:neurotransmitter biosynthetic process, P:xenobiotic metabolic process, "F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor", F:oxidoreductase activity, F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
UniProt3D-structure, Acetylation, Alternative splicing, Complete proteome, Direct protein sequencing, Mitochondrion, NAD, Oxidoreductase, Polymorphism, Reference proteome, Transit peptide
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.893.61E-0220136355
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_2_days_follow-up) (Multiple sclerosis)0.880.0395089120136355
Exp21346816Homo sapiens12Blood MS (Multiple sclerosis)0.770.02008221346816
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1a_3_month_follow-up) (Multiple sclerosis)0.813.79E-0221886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)0.790.02773421886806
Exp21886806Homo sapiens12Blood RRMS_(IFN-Beta-1b_24_month_follow-up) (Multiple sclerosis)0.750.01339821886806
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)1.365.59E-0422021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.371.61E-0722252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)0.417.12E-0722252466
Exp23895517AHomo sapiens19BloodT-cellsRRMS_(relapsing-remitting_MS) (Multiple sclerosis)0.901.52E-0223895517

Compile date 09-07-2016© MuScle project