MuScle-logoMuScle - Molecule ID B0551

geneALDH7A1, ATQ1
nameAldehyde dehydrogenase family 7 member A1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AL7A1_HUMANP49419ENSG00000164904501Hs.483239107323, 266100

Functions and classifications

GOC:cytosol, C:mitochondrial matrix, C:nucleus, F:aldehyde dehydrogenase (NAD) activity, F:betaine-aldehyde dehydrogenase activity, F:L-aminoadipate-semialdehyde dehydrogenase activity, P:cellular aldehyde metabolic process, P:cellular nitrogen compound metabolic process, P:glycine betaine biosynthetic process from choline, P:lysine catabolic process, P:sensory perception of sound, "F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor", F:oxidoreductase activity
UniProt3D-structure, Acetylation, Alternative splicing, Complete proteome, Cytoplasm, Disease mutation, Epilepsy, Mitochondrion, NAD, Nucleus, Oxidoreductase, Polymorphism, Reference proteome, Transit peptide
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_6_month_follow-up) (Multiple sclerosis)0.714.45E-0217467740
Exp20136355Homo sapiens50Blood RRMS_(rIFN-Beta-1b_1_month_follow-up) (Multiple sclerosis)0.642.74E-0220136355
Exp21216829Homo sapiens8BloodCD4+RRMS_(CD4+) (Multiple sclerosis)0.340.016462621216829
Exp21216829Homo sapiens8BloodCD4+RRMS_(CD4+) (Multiple sclerosis)9.000.048540821216829
Exp21346816Homo sapiens12Blood MS (Multiple sclerosis)0.550.00086321346816
Exp22252466AHomo sapiens13BloodCD34- HPCRRMS_SPMS (Multiple sclerosis)1.291.46E-0222252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)2.412.67E-1022252466
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)5.035.72E-1322252466

Compile date 09-07-2016© MuScle project