MuScle-logoMuScle - Molecule ID B0540

geneALDH1L1, FTHFD
nameAldehyde dehydrogenase 1 family, member L1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AL1L1_HUMANO75891ENSG0000014490810840Hs.434435600249

Functions and classifications

GOC:mitochondrion, F:catalytic activity, F:formyltetrahydrofolate dehydrogenase activity, F:hydroxymethyl-, formyl- and related transferase activity, F:methyltransferase activity, F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, P:10-formyltetrahydrofolate catabolic process, P:biosynthetic process, P:methylation, P:one-carbon metabolic process, "F:formyltetrahydrofolate dehydrogenase activity, F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor", P:methylation", "F:hydroxymethyl-, formyl- and related transferase activity, P:biosynthetic process", "C:cytoplasm, F:oxidoreductase activity
UniProt3D-structure, Alternative splicing, Complete proteome, Cytoplasm, NADP, One-carbon metabolism, Oxidoreductase, Phosphopantetheine, Phosphoprotein, Polymorphism, Reference proteome
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22491253Homo sapiens7BloodRRMS_(High_Sema4A) (Multiple sclerosis)0.360.0406986722491253
Exp22491253Homo sapiens7BloodRRMS_(Low_Sema4A) (Multiple sclerosis)0.330.013421222491253

Compile date 09-07-2016© MuScle project