MuScle-logoMuScle - Molecule ID B0538

geneALDH1A3, ALDH6
nameAldehyde dehydrogenase 6
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AL1A3_HUMANP47895ENSG00000184254220Hs.459538600463, 615113

Functions and classifications

GOC:cytoplasm, F:aldehyde dehydrogenase (NAD) activity, F:aldehyde dehydrogenase [NAD(P)+] activity, F:NAD+ binding, F:protein homodimerization activity, F:thyroid hormone binding, P:embryonic eye morphogenesis, P:face development, P:inner ear morphogenesis, P:locomotory behavior, P:neuromuscular process controlling balance, P:nucleus accumbens development, P:olfactory pit development, P:optic cup morphogenesis involved in camera-type eye development, P:positive regulation of apoptotic process, P:retinal metabolic process, P:retinoic acid biosynthetic process, P:retinoic acid metabolic process, P:retinol metabolic process, P:righting reflex, F:oxidoreductase activity, "F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor", P:kidney development, P:pituitary gland development, P:response to drug
UniProtAcetylation, Complete proteome, Cytoplasm, Direct protein sequencing, Disease mutation, Microphthalmia, NAD, Oxidoreductase, Polymorphism, Reference proteome
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp17467740Homo sapiens10Blood RRMS_(IFN-Beta-1a_1_day_follow-up) (Multiple sclerosis)0.504.77E-0217467740
Exp22252466AHomo sapiens13BloodCD34+ HPCRRMS_SPMS (Multiple sclerosis)0.860.028244322252466

Compile date 09-07-2016© MuScle project