MuScle-logoMuScle - Molecule ID B0537

nameRetinal dehydrogenase 2
speciesHomo sapiens

Molecule reference


Functions and classifications

GOC:cytoplasm, C:cytosol, C:nucleus, C:perinuclear region of cytoplasm, F:3-chloroallyl aldehyde dehydrogenase activity, F:retinal binding, F:retinal dehydrogenase activity, P:9-cis-retinoic acid biosynthetic process, P:anterior/posterior pattern specification, P:blood vessel development, P:cardiac muscle tissue development, P:cellular response to retinoic acid, P:determination of bilateral symmetry, P:embryonic camera-type eye development, P:embryonic digestive tract development, P:embryonic forelimb morphogenesis, P:face development, P:heart morphogenesis, P:hindbrain development, P:kidney development, P:liver development, P:lung development, P:midgut development, P:morphogenesis of embryonic epithelium, P:negative regulation of cell proliferation, P:neural crest cell development, P:neural tube development, P:neuron differentiation, P:pancreas development, P:pituitary gland development, P:positive regulation of apoptotic process, P:positive regulation of cell proliferation, P:positive regulation of gene expression, P:proximal/distal pattern formation, P:regulation of endothelial cell proliferation, P:response to cytokine, P:response to estradiol, P:response to vitamin A, P:retinal metabolic process, P:retinoic acid metabolic process, P:retinoic acid receptor signaling pathway, P:retinol metabolic process, P:ureter maturation, P:vitamin A metabolic process, "C:cytoplasm, F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor", "F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor", P:oxidation-reduction process, P:response to cytokine stimulus, P:response to estradiol stimulus
UniProtAlternative splicing, Complete proteome, Cytoplasm, NAD, Oxidoreductase, Polymorphism, Reference proteome, Phosphoprotein
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceDiseaseFold change in diseaseP-valuePubMed/DOI
Exp20136355Homo sapiens50BloodRRMS_(rIFN-Beta-1b_12_month_follow-up) (Multiple sclerosis)1.650.0231000820136355
Exp22491253Homo sapiens7BloodRRMS_(High_Sema4A) (Multiple sclerosis)0.270.0148961322491253
Exp22491253Homo sapiens7BloodRRMS_(Low_Sema4A) (Multiple sclerosis)2.940.026906222491253

Compile date 09-07-2016© MuScle project