MuScle-logoMuScle - Molecule ID B0534

geneAKT1S1, PRAS40
nameProline-rich AKT1 substrate 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AKTS1_HUMANQ96B36ENSG0000020467384335Hs.515542610221

Functions and classifications

GOC:cytosol, C:nucleus, C:protein complex, P:epidermal growth factor receptor signaling pathway, P:Fc-epsilon receptor signaling pathway, P:fibroblast growth factor receptor signaling pathway, P:innate immune response, P:negative regulation of cell size, P:negative regulation of protein kinase activity, P:negative regulation of TOR signaling, P:neurotrophin TRK receptor signaling pathway, P:phosphatidylinositol-mediated signaling, P:regulation of neuron apoptotic process, C:cytosolic part, P:negative regulation of TOR signaling cascade, P:nerve growth factor receptor signaling pathway
UniProtAlternative splicing, Complete proteome, Cytoplasm, Phosphoprotein, Polymorphism, Reference proteome
PADBUK: unknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valuePubMed/DOI
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.742.14E-0322021740
Exp22021740Homo sapiens27Blood MS (Multiple sclerosis)0.891.86E-0222021740
Exp22252466AHomo sapiens16BloodCD34+/CD34- HPCRRMS_SPMS (Multiple sclerosis)1.335.42E-0322252466
Exp22491253Homo sapiens7Blood RRMS_(High_Sema4A) (Multiple sclerosis)4.660.0096023222491253

Compile date 09-07-2016© MuScle project